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Vitamin D May Help to Slow Down Fibroid Growth

Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase.

Authors: Sharan C, Halder SK, Thota C, Jaleel T, Nair S, Al-Hendy A.

Study From: Meharry Medical College, Nashville, Tennessee

Journal: Fertility and Sterility, 2010, Aug 23. E-pub

Problem: Women are looking for something they can do to control fibroid growth. Dietary changes and vitamin supplements would be one possible thing they can easily modify.

Laboratory Study: Human fibroid cell cultures were treated with vitamin D and the effect of vitamin D on fibroid genes and proteins was measured.

Results: Vitamin D interfered with the way human fibroid cells make enzymes that either use or block estrogen and inhibited the growth of fibroid cells by 47%.

Authors’ Conclusions: Since Vitamin D inhibits growth of human fibroid cells a deficiency of vitamin D might allow fibroids to grow. The authors reference another article that found that while 45% of African-American women have vitamin D deficiency, only 4% of white women have this deficiency.

Dr. Parker’s Comments: While it is always good to be cautious when interpreting laboratory studies, vitamin D has also been shown to regulate cell growth and inhibit cancer cells. It also helps the body absorb calcium. And, when taken in recommended doses (800-1,000 units per day), the side-effects and risks appear to be almost non-existent. So, even though these results are very preliminary, vitamin D might be worth a try

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2 Comments

  1. Kathy
    Posted June 30, 2011 at 10:31 pm | Permalink

    Another fibroid sufferer suggested to me that it’s especially important to take vitamin D3. Is that true? Would the reportedly plant-derived D2 be just as advisable? I’ve been taking D3 for a while, but I’m trying to avoid animal products now and have heard that D3 is taken from the skin of animals. Can you give me any advice on this? Thanks!

  2. Posted July 4, 2011 at 5:59 pm | Permalink

    K,

    The specific type of vitamin D in this study was D3. Sorry, but I am not aware of any other study for D2 and I do not know the biochemistry to be able to tell you even if it should theoretically work.

    Bill Parker, MD

Fibroid Doctor William H. Parker

Dr. William H. Parker is a board-certified Fellow in the American College of Obstetricians and Gynecologists. Dr. Parker is an internationally recognized expert in fibroid surgery and research. Based in San Diego, California, he is considered one of the best fibroid surgeons for abdominal and laparoscopic myomectomy in the United States and abroad. He has been chosen for Best Doctors in America and Top Doctors every year beginning in the late 90's.

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