Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase.
Authors: Sharan C, Halder SK, Thota C, Jaleel T, Nair S, Al-Hendy A.
Study From: Meharry Medical College, Nashville, Tennessee
Journal: Fertility and Sterility, 2010, Aug 23. E-pub
Problem: Women are looking for something they can do to control fibroid growth. Dietary changes and vitamin supplements would be one possible thing they can easily modify.
Laboratory Study: Human fibroid cell cultures were treated with vitamin D and the effect of vitamin D on fibroid genes and proteins was measured.
Results: Vitamin D interfered with the way human fibroid cells make enzymes that either use or block estrogen and inhibited the growth of fibroid cells by 47%.
Authors’ Conclusions: Since Vitamin D inhibits growth of human fibroid cells a deficiency of vitamin D might allow fibroids to grow. The authors reference another article that found that while 45% of African-American women have vitamin D deficiency, only 4% of white women have this deficiency.
Dr. Parker’s Comments: While it is always good to be cautious when interpreting laboratory studies, vitamin D has also been shown to regulate cell growth and inhibit cancer cells. It also helps the body absorb calcium. And, when taken in recommended doses (800-1,000 units per day), the side-effects and risks appear to be almost non-existent. So, even though these results are very preliminary, vitamin D might be worth a try
2 Comments