Oral tranexamic acid treatment was well tolerated and significantly improved both menstrual blood loss and health-related quality of life in women with heavy menstrual bleeding.


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Oral tranexamic acid treatment was well tolerated and significantly improved both menstrual blood loss and health-related quality of life in women with heavy menstrual bleeding.
Journal: Obstetetrics and Gynecology. 2010 Sep;116(3):641-52. Authors: Spies JB, Bradley LD, Guido R, Maxwell GL, Levine BA, Coyne K. Study from: Georgetown University Hospital Department of Radiology, Washington, DC Problem: Despite the very common occurrence of fibroids, very few studies have evaluated the severity of symptoms caused by uterine fibroids, their effect on health-related quality-of-life, [...]
Journal: Obstet Gynecol. 2010 Nov;116(5):1056-63. Authors: Stout MJ, Odibo AO, Graseck AS, Macones GA, Crane JP, Cahill AG. Study from: Washington University, St Louis, Missouri Problem: Numerous studies have been conducted to see if the presence of fibroids during pregnancy affects the outcome of the pregnancy or the health of the baby. Most of these [...]
Journal: Fertil Steril. 2010 Sep 24. [Epub ahead of print] Authors: Pisco JM, Duarte M, Bilhim T, Cirurgião F, Oliveira AG. Study from: Department of Radiology, St. Louis Hospital; New University of Lisbon, Portugal. Problem: The safety of pregnancy following embolization (UAE) is uncertain because there have been few publications examining this issue. Study: In [...]
Women who do not have the BRCA cancer gene or a strong family history of ovarian cancer should strongly consider keeping their ovaries, especially if they are not menopausal.
At the beginning of the study, the women filled out questionnaires asking about their level of activity, energy level, sexual function, pain, social functioning, general health and mental health. Six and 12 months later, questionnaires showed that, after any of the three fibroid treatments, most women felt as good as women without fibroids. At 12 months, women who had a hysterectomy had fewer symptoms (no bleeding) than women who had myomectomies or UAE.
Vitamin D interfered with the way human fibroid cells make enzymes that either use or block estrogen and inhibited the growth of fibroid cells by 47%.
Dr Parker’s Comments: There have been very few studies examining the effect of fibroids on women’s sexual satisfaction, and even fewer on the effects of different treatment options on sexual satisfaction. For that reason, the current findings that women with fibroids have more pelvic pain with intercourse and that myomectomy appears to help many of these women are good steps in helping women understand their symptoms. Similar research with regard to other treatment options including uterine artery embolization, focused ultrasound, mefipristone, etc, are sorely needed.
A Qualitative Comparison of Women’s Attitudes Towards Hysterectomy and Myomectomy Julie Askew PhD. Healthcare for Women International 2009;30:728-42. Study: Eighteen women, ages 31-49, who suffered from symptoms of fibroids and who had undergone a hysterectomy or myomectomy in the past 2 years were interviewed by the author. All of the women had further education or [...]
fibroids rarely interfere with pregnancy and have no direct effect on the baby
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Dr. William H. Parker is a board-certified Fellow in the American College of Obstetricians and Gynecologists. Dr. Parker is an internationally recognized expert in fibroid surgery and research. Based in Los Angeles, California, he is considered one of the best fibroid surgeons for abdominal and laparoscopic myomectomy in the United States and abroad. He has been chosen for Best Doctors in America and Top Doctors every year beginning in the late 90's.
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