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Category Archives: Recent Fibroid Research

Dr. Parker will post summaries of recent fibroid research every week and will comment about the significance of the research and how it applies to women with fibroids. Feel free to add your comments or thoughts.

NOTE: Please click on the links below to read the full post.

How Soon Can You Get Pregnant after a Myomectomy?

I often get asked this question, “how soon after my myomectomy can we start trying to get pregnant”? Along the way in my training and ever since, I have heard all kinds of answers from my professors and colleagues:“women need to wait a year” ; “six months”; “three months”; “two months”. None of these answers […]

This is Why the Medical Literature is Confusing!

Adverse obstetric outcomes associated with sonographically identified large uterine fibroids. Authors: Shavell VI, Thakur M, Sawant A, Kruger ML, Jones TB, Singh M, Puscheck EE, Diamond MP. From: Wayne State University, Detroit, Michigan Journal: Fertility Sterility. 2012 Jan;97:107-10 Problem: Studies show mixed results about whether fibroids affect pregnancy or delivery. Many studies are poorly conducted […]

New Oral Medication Tested for Fibroids

Title: Ulipristal Acetate versus Placebo for Fibroid Treatment before Surgery Journal: New England Journal of Medicine, February, 2012 Authors: Donnez J, Tatarchuk T, Bouchard P, and others Study from: Brussels, Russia, France, Romania, Hungary, Switzerland, England Problem: There are no currently effective and safe pills for treatment of uterine fibroid symptoms. Study: Women with heavy […]

Hysterectomy Improves Sexual Response? Addressing a Crucial Omission in the Literature

Journal: The Journal of Minimally Invasive Gynecology, Volume 18, Pages 288-295, May 2011 Authors: Barry R. Komisaruk, Eleni Frangos, Beverly Whipple Study from: University of Medicine and Dentistry of New Jersey Problem: The prevailing view in the medical literature is that hysterectomy improves the quality of life. This is based on claims that hysterectomy relieves […]

Using MRI to Determine Surgical Treatment Options for Women with Fibroids

The utility of MRI for the surgical treatment of women with uterine fibroid tumors Journal: American Journal of Obstetrics and Gynecology (in press, available now on-line for subscribers) Authors: William Parker From: UCLA School of Medicine, Los Angeles, CA. Problem: Fibroids can usually be diagnosed by pelvic examination and ultrasound, but neither gives us exact […]

How do Fibroids Cause Infertility and Heavy Menstrual Bleeding?

Leiomyoma simultaneously impair endometrial BMP-2-mediated decidualization and anticoagulant expression through secretion of TGF-β3. Journal: Journal of Clinical Endocrinology and Metabolism. 2011;96:412-21. Authors: Sinclair DC, Mastroyannis A, Taylor HS. Study from: Yale University School of Medicine Problem: Women with submucous fibroids have decreased fertility, increased miscarriage rates, and heavy menstrual bleeding. Why this happens has not […]

Predicting Fibroid Growth: Two Studies

This is the first study to accurately track fibroid growth, both in different women and different fibroids in the same woman. I (and other gynecologists) have been telling women for 30 years that fibroids do not get smaller until after menopause – this study proves that idea wrong. I have also been telling women that fibroid growth is unpredictable, some fibroids grow slowly, others fast and others go through growth spurts and then slow down.

Randomised comparison of uterine artery embolisation (UAE) with surgical treatment in patients with symptomatic uterine fibroids (REST trial): 5-year results.

Authors: Moss J, Cooper K, Khaund A, Murray L, Murray G, Wu O, Craig L, Lumsden M. Journal: British Journal of Obstetrics and Gynecology  2011;118:936–944. Study From: North Glasgow University Hospitals, Glasgow, UK Problem: Women with uterine fibroids now have a number of treatment options available. Very few studies have compared the results of treatment […]

Fibroids within the Uterine Wall (intramural) Do Not Decrease Fertility

Title: Fibroids not encroaching the endometrial cavity and IVF success rate: a prospective study. Journal: Human Reproduction. 2011;26:834-9. Authors: Somigliana E, De Benedictis S, Vercellini P, Nicolosi AE, Benaglia L, Scarduelli C, Ragni G, Fedele L. Study from: Department of Obset/Gynecol-Fondazione Cà Granda, Milano, Italy. Problem: Other studies show that fibroids that bulge into the […]

The effect of myomectomy on health-related quality of life of women with fibroids

Despite 50 years of myomectomy surgery, this is the first study to carefully evaluate whether women actually feel better as a result of having a myomectomy. So, now we have studies of women following treatment with UAE, myomectomy and hysterectomy that show improvement in quality-of-life. As I said on an earlier post, this leaves the decision about which treatment to have up to each woman, since these three treatments all help. And, since I perform mostly myomectomy surgery, this study validates what my patients have been telling me for years – they feel great after myomectomy.


Disclaimer: The ideas, procedures and suggestions contained on this web site are not intended as a substitute for consulting with your physician. All matters regarding your health require medical supervision.

Fibroid Doctor William H. Parker

Dr. William H. Parker is a board-certified Fellow in the American College of Obstetricians and Gynecologists. Dr. Parker is an internationally recognized expert in fibroid surgery and research. Based in San Diego, California, he is considered one of the best fibroid surgeons for abdominal and laparoscopic myomectomy in the United States and abroad. He has been chosen for Best Doctors in America and Top Doctors every year beginning in the late 90's.

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